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Hepatitis B virus integration in hepatocellular carcinoma DNA: duplication of cellular flanking sequences at the integration site.

The integrated form of hepatitis B virus (HBV) in the human hepatoma cell line huH2-2 and its cellular counterpart sequence have been cloned and analyzed. Blot hybridization analysis and nucleotide sequencing indicated that a single copy of the 1895-base-pair (bp) subgenomic region of HBV DNA, spann...

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Autores principales: Yaginuma, K, Kobayashi, M, Yoshida, E, Koike, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1985
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC391120/
https://ncbi.nlm.nih.gov/pubmed/2989822
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