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Tumor-associated mutations of rat mitochondrial transfer RNA genes.

Mitochondrial DNA is a sensitive target of chemical carcinogens (Backer and Weinstein (1980) Science 209, 297-299), suggesting that mutations of the mitochondrial genome occur in tumor cells. We examined this point by comparing mitochondrial DNA sequences in four rat tumors with those of normal rat...

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Autori principali: Taira, M, Yoshida, E, Kobayashi, M, Yaginuma, K, Koike, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1983
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC325825/
https://ncbi.nlm.nih.gov/pubmed/6300770
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