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Tumor-associated mutations of rat mitochondrial transfer RNA genes.
Mitochondrial DNA is a sensitive target of chemical carcinogens (Backer and Weinstein (1980) Science 209, 297-299), suggesting that mutations of the mitochondrial genome occur in tumor cells. We examined this point by comparing mitochondrial DNA sequences in four rat tumors with those of normal rat...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1983
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC325825/ https://ncbi.nlm.nih.gov/pubmed/6300770 |
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