Neisseria meningitidis Native Outer Membrane Vesicles Containing Different Lipopolysaccharide Glycoforms as Adjuvants for Meningococcal and Nonmeningococcal Antigens

We evaluated the adjuvant effect of a modified glycoform of lipopolysaccharide (LPS) (LgtB-LpxL1) compared to that of the nonmodified glycoform Lpxl1 serogroup B meningococcal H44/76 native outer membrane vesicles (nOMVs) on immune responses to vaccination with the recombinant meningococcal protein,...

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Autors principals: Nagaputra, Jerry C., Rollier, Christine S., Sadarangani, Manish, Hoe, J. Claire, Mehta, Ojas Hrakesh, Norheim, Gunnstein, Saleem, Muhammad, Chan, Hannah, Derrick, Jeremy P., Feavers, Ian, Pollard, Andrew J., Moxon, E. Richard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910940/
https://ncbi.nlm.nih.gov/pubmed/24351756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00561-13
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