Hypoglycin A: A Specific Inhibitor of Isovaleryl CoA Dehydrogenase

Evidence is presented for the specific in vivo and in vitro inhibition of isovaleryl CoA dehydrogenation by hypoglycin A and its derivative, α-ketomethylenecyclopropylpropionic acid. α-Methylbutyryl CoA dehydrogenation was also impaired, but the degree of inhibition was much lower. Isobutyryl CoA de...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Tanaka, Kay, Miller, Edith M., Isselbacher, Kurt J.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1971
Matèries:	Biological Sciences: Medical Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5276292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.1.20
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