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Hypoglycin A: A Specific Inhibitor of Isovaleryl CoA Dehydrogenase

Evidence is presented for the specific in vivo and in vitro inhibition of isovaleryl CoA dehydrogenation by hypoglycin A and its derivative, α-ketomethylenecyclopropylpropionic acid. α-Methylbutyryl CoA dehydrogenation was also impaired, but the degree of inhibition was much lower. Isobutyryl CoA de...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Tanaka, Kay, Miller, Edith M., Isselbacher, Kurt J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1971
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Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5276292/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.1.20
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