Urinary Concentrations and Antibacterial Activities of Nitroxoline at 250 Milligrams versus Trimethoprim at 200 Milligrams against Uropathogens in Healthy Volunteers

Because of the increasing bacterial resistance of uropathogens against standard antibiotics, such as trimethoprim (TMP), older antimicrobial drugs, such as nitroxoline (NTX), should be reevaluated. This randomized crossover study investigated the urinary concentrations of parent drugs and their meta...

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Main Authors: Wagenlehner, Florian M. E., Münch, Fabian, Pilatz, Adrian, Bärmann, Birte, Weidner, Wolfgang, Wagenlehner, Christine M., Straubinger, Marion, Blenk, Holger, Pfister, Wolfgang, Kresken, Michael, Naber, Kurt G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910821/
https://ncbi.nlm.nih.gov/pubmed/24217699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02147-13
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