Concentrations in Plasma, Urinary Excretion, and Bactericidal Activity of Linezolid (600 Milligrams) versus Those of Ciprofloxacin (500 Milligrams) in Healthy Volunteers Receiving a Single Oral Dose

In a randomized crossover study, 12 volunteers (6 males, 6 females) received a single oral dose of 600 mg of linezolid or 500 mg of ciprofloxacin to assess the concentrations in plasma (up to 24 h), urinary excretion (by high-pressure liquid chromatography), and bactericidal titers in urine (UBT) at...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wagenlehner, Florian M. E., Wydra, Stephan, Onda, Hajime, Kinzig-Schippers, Martina, Sörgel, Fritz, Naber, Kurt G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3789-3794.2003
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