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Kinetics of ofloxacin and its metabolites in cerebrospinal fluid after a single intravenous infusion of 400 milligrams of ofloxacin.

Ofloxacin has been reported to diffuse readily into the cerebrospinal fluid (CSF) in subjects with both inflamed and uninflamed meninges. However, with moderately susceptible bacteria, ofloxacin concentrations in CSF may be subtherapeutic after administration of an intravenous (i.v.) dose of 200 mg....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Nau, R, Kinzig, M, Dreyhaupt, T, Kolenda, H, Sörgel, F, Prange, H W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7986019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.8.1849
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