Structure of a kinesin microtubule depolymerization machine

With their ability to depolymerize microtubules (MTs), KinI kinesins are the rogue members of the kinesin family. Here we present the 1.6 Å crystal structure of a KinI motor core from Plasmodium falciparum, which is sufficient for depolymerization in vitro. Unlike all published kinesin structures to...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Shipley, Krista, Hekmat-Nejad, Mohammad, Turner, Jennifer, Moores, Carolyn, Anderson, Robert, Milligan, Ronald, Sakowicz, Roman, Fletterick, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2004
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391071/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15029249/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600165
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