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Structure of a kinesin microtubule depolymerization machine

With their ability to depolymerize microtubules (MTs), KinI kinesins are the rogue members of the kinesin family. Here we present the 1.6 Å crystal structure of a KinI motor core from Plasmodium falciparum, which is sufficient for depolymerization in vitro. Unlike all published kinesin structures to...

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Detalhes bibliográficos
Main Authors: Shipley, Krista, Hekmat-Nejad, Mohammad, Turner, Jennifer, Moores, Carolyn, Anderson, Robert, Milligan, Ronald, Sakowicz, Roman, Fletterick, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC391071/
https://ncbi.nlm.nih.gov/pubmed/15029249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600165
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