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Lesion (in)tolerance reveals insights into DNA replication fidelity

The initial encounter of an unrepaired DNA lesion is likely to be with a replicative DNA polymerase, and the outcome of this event determines whether an error-prone or error-free damage avoidance pathway is taken. To understand the atomic details of this critical encounter, we have determined the cr...

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Autori principali: Freisinger, Eva, Grollman, Arthur P, Miller, Holly, Kisker, Caroline
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC391067/
https://ncbi.nlm.nih.gov/pubmed/15057282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600158
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