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The mitochondrial ARTS protein promotes apoptosis through targeting XIAP

ARTS is an unusual septin-like mitochondrial protein that was originally shown to mediate TGF-beta-induced apoptosis. Recently, we found that ARTS is also important for cell killing by other pro-apoptotic factors, such as arabinoside, etoposide, staurosporine and Fas. In Drosophila, the IAP antagoni...

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Detalhes bibliográficos
Main Authors: Gottfried, Yossi, Rotem, Asaf, Lotan, Rona, Steller, Hermann, Larisch, Sarit
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC391065/
https://ncbi.nlm.nih.gov/pubmed/15029247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600155
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