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Structure of the Helicobacter pylori CagA oncoprotein bound to the human tumor suppressor ASPP2

The Cytotoxin associated gene A (CagA) protein of Helicobacter pylori is associated with increased virulence and risk of cancer. Recent proteomic studies have demonstrated an association of CagA with the human tumor suppressor Apoptosis-stimulating Protein of p53-2 (ASPP2). We present here a genetic...

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Bibliografiske detaljer
Main Authors: Nešić, Dragana, Buti, Ludovico, Lu, Xin, Stebbins, C. Erec
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910616/
https://ncbi.nlm.nih.gov/pubmed/24474782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320631111
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