Chlorotoxin-Fc Fusion Inhibits Release of MMP-2 from Pancreatic Cancer Cells

Chlorotoxin (CTX) is a 36-amino acid peptide derived from Leiurus quinquestriatus (scorpion) venom, which inhibits low-conductance chloride channels in colonic epithelial cells. It has been reported that CTX also binds to matrix metalloproteinase-2 (MMP-2), membrane type-1 MMP, and tissue inhibitor...

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Detalhes bibliográficos
Main Authors: El-Ghlban, Samah, Kasai, Tomonari, Shigehiro, Tsukasa, Yin, Hong Xia, Sekhar, Sreeja, Ida, Mikiko, Sanchez, Anna, Mizutani, Akifumi, Kudoh, Takayuki, Murakami, Hiroshi, Seno, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910484/
https://ncbi.nlm.nih.gov/pubmed/24511528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/152659
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