Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis

Chlorotoxin is a 36-amino acid peptide derived from Leiurus quinquestriatus (scorpion) venom, which has been shown to inhibit low-conductance chloride channels in colonic epithelial cells. Chlorotoxin also binds to matrix metalloproteinase-2 and other proteins on glioma cell surfaces. Glioma cells a...

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Detalhes bibliográficos
Main Authors: Kasai, Tomonari, Nakamura, Keisuke, Vaidyanath, Arun, Chen, Ling, Sekhar, Sreeja, El-Ghlban, Samah, Okada, Masashi, Mizutani, Akifumi, Kudoh, Takayuki, Murakami, Hiroshi, Seno, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523153/
https://ncbi.nlm.nih.gov/pubmed/23304519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/975763
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