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The role of CDK5 and GSK3B kinases in hyperphosphorylation of microtubule associated protein tau (MAPT) in Alzheimer's disease

Alzheimer's disease is the most common form of dementia. Abnormal hyperphosphorylation of Microtubule associated protein tau (MAPT) is one of the hallmarks of Alzheimer's disease and related tau pathies. CDK5 and GSK3B are the two main protein kinases that have an important role in the abn...

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Detalhes bibliográficos
Main Authors: Jayapalan, Saranya, Natarajan, Jeyakumar
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910359/
https://ncbi.nlm.nih.gov/pubmed/24497730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630091023
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