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The role of CDK5 and GSK3B kinases in hyperphosphorylation of microtubule associated protein tau (MAPT) in Alzheimer's disease

Alzheimer's disease is the most common form of dementia. Abnormal hyperphosphorylation of Microtubule associated protein tau (MAPT) is one of the hallmarks of Alzheimer's disease and related tau pathies. CDK5 and GSK3B are the two main protein kinases that have an important role in the abn...

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Autors principals: Jayapalan, Saranya, Natarajan, Jeyakumar
Format: Artigo
Idioma:Inglês
Publicat: Biomedical Informatics 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910359/
https://ncbi.nlm.nih.gov/pubmed/24497730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630091023
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