Immobilization with Atrophy Induces Increased Expression of Neuronal Nicotinic α7 Acetylcholine Receptors in Muscle Contributing to Neurotransmission

BACKGROUND: Mature acetylcholine receptor (AChR) isoform normally mediates muscle contraction. The hypothesis that α7AChRs upregulate during immobilization and contribute to neurotransmission was tested pharmacologically using specific blockers to mature (waglerin-1), immature (αA-OIVA), and α7AChRs...

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Main Authors: Lee, Sangseok, Yang, Hong-seuk, Sasakawa, Tomoki, Khan, Mohammed A. S., Khatri, Ashok, Kaneki, Masao, Jeevendra Martyn, J. A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910258/
https://ncbi.nlm.nih.gov/pubmed/24126263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000025
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