PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis

BACKGROUND & AIMS: Hepatic gluconeogenesis helps maintain systemic energy homeostasis by compensating for discontinuities in nutrient supply. Liver specific deletion of cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C) abolishes gluconeogenesis from mitochondrial substrates, deregulates lipi...

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Main Authors: Méndez-Lucas, Andrés, Duarte, João, Sunny, Nishanth E., Satapati, Santhosh, He, TianTeng, Fu, Xiaorong, Bermúdez, Jordi, Burgess, Shawn C., Perales, Jose C.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910155/
https://ncbi.nlm.nih.gov/pubmed/23466304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.02.020
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