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Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

Approximately one-third of the U.S. population has nonalcoholic fatty liver disease (NAFLD), a condition closely associated with insulin resistance and increased risk of liver injury. Dysregulated mitochondrial metabolism is central in these disorders, but the manner and degree of dysregulation are...

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Detalhes bibliográficos
Main Authors: Sunny, Nishanth E., Parks, Elizabeth J., Browning, Jeffrey D., Burgess, Shawn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658280/
https://ncbi.nlm.nih.gov/pubmed/22152305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.11.004
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