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Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.

A method that allows the specific cloning of DNA fragments absent from patients homozygous or hemizygous for chromosomal deletions is described. The method involves phenol-accelerated competitive DNA reassociation and subsequent molecular cloning of appropriately reassociated molecules. The deletion...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kunkel, L M, Monaco, A P, Middlesworth, W, Ochs, H D, Latt, S A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2991893/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.14.4778
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