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Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.

A method that allows the specific cloning of DNA fragments absent from patients homozygous or hemizygous for chromosomal deletions is described. The method involves phenol-accelerated competitive DNA reassociation and subsequent molecular cloning of appropriately reassociated molecules. The deletion...

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Autori principali: Kunkel, L M, Monaco, A P, Middlesworth, W, Ochs, H D, Latt, S A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC390988/
https://ncbi.nlm.nih.gov/pubmed/2991893
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