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Cellular senescence and its effector programs

Cellular senescence is a stress response that accompanies stable exit from the cell cycle. Classically, senescence, particularly in human cells, involves the p53 and p16/Rb pathways, and often both of these tumor suppressor pathways need to be abrogated to bypass senescence. In parallel, a number of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Salama, Rafik, Sadaie, Mahito, Hoare, Matthew, Narita, Masashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909793/
https://ncbi.nlm.nih.gov/pubmed/24449267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.235184.113
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