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Histone H3.3 and its proteolytically processed form drive a cellular senescence program
The process of cellular senescence generates a repressive chromatin environment, however, the role of histone variants and histone proteolytic cleavage in senescence remains unclear. Using models of oncogene-induced and replicative senescence, here we report novel histone H3 tail cleavage events med...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4235654/ https://ncbi.nlm.nih.gov/pubmed/25394905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6210 |
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