Potential Role of BNIP3 in Cardiac Remodeling, Myocardial Stiffness and Endoplasmic Reticulum-Mitochondrial Calcium Homeostasis in Diastolic and Systolic Heart Failure

BACKGROUND: We have shown that BNIP3 expression is significantly increased in HF. In this study, we tested the effects of BNIP3 manipulation in HF. METHODS AND RESULTS: In a rat model of pressure overload HF, BNIP3 knockdown significantly decreased LV volumes with significant improvement in LV diast...

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Detaylı Bibliyografya
Asıl Yazarlar: Chaanine, Antoine H., Gordon, Ronald E., Kohlbrenner, Erik, Benard, Ludovic, Jeong, Dongtak, Hajjar, Roger J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909701/
https://ncbi.nlm.nih.gov/pubmed/23508759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.000200
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