Potential Role of BNIP3 in Cardiac Remodeling, Myocardial Stiffness and Endoplasmic Reticulum-Mitochondrial Calcium Homeostasis in Diastolic and Systolic Heart Failure

BACKGROUND: We have shown that BNIP3 expression is significantly increased in HF. In this study, we tested the effects of BNIP3 manipulation in HF. METHODS AND RESULTS: In a rat model of pressure overload HF, BNIP3 knockdown significantly decreased LV volumes with significant improvement in LV diast...

Full description

Saved in:
Bibliographic Details
Main Authors: Chaanine, Antoine H., Gordon, Ronald E., Kohlbrenner, Erik, Benard, Ludovic, Jeong, Dongtak, Hajjar, Roger J.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909701/
https://ncbi.nlm.nih.gov/pubmed/23508759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.000200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items