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Potential Role of BNIP3 in Cardiac Remodeling, Myocardial Stiffness and Endoplasmic Reticulum-Mitochondrial Calcium Homeostasis in Diastolic and Systolic Heart Failure
BACKGROUND: We have shown that BNIP3 expression is significantly increased in HF. In this study, we tested the effects of BNIP3 manipulation in HF. METHODS AND RESULTS: In a rat model of pressure overload HF, BNIP3 knockdown significantly decreased LV volumes with significant improvement in LV diast...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909701/ https://ncbi.nlm.nih.gov/pubmed/23508759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.000200 |
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