The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.

A Saccharomyces cerevisiae strain with a disrupted yeast cadmium resistance factor (YCF1) gene (DTY168) is hypersensitive to cadmium. YCF1 resembles the human multidrug resistance-associated protein MRP (63% amino acid similarity), which confers resistance to various cytotoxic drugs by lowering the...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Tommasini, R, Evers, R, Vogt, E, Mornet, C, Zaman, G J, Schinkel, A H, Borst, P, Martinoia, E
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6743
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