The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1.
A Saccharomyces cerevisiae strain with a disrupted yeast cadmium resistance factor (YCF1) gene (DTY168) is hypersensitive to cadmium. YCF1 resembles the human multidrug resistance-associated protein MRP (63% amino acid similarity), which confers resistance to various cytotoxic drugs by lowering the...
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| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6743 |
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