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Helicobacter pylori activates NF-κB by inducing Ubc13-mediated ubiquitination of lysine 158 of TAK1

The Helicobacter pylori virulence factor CagA targets a variety of host proteins to alter different cellular responses, including the induction of pro-inflammatory cytokines. We have previously shown that CagA-facilitated lysine 63-linked ubiquitination of TAK1 is essential for the H. pylori-induced...

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Detalhes bibliográficos
Main Authors: Lamb, Acacia, Chen, JinJing, Blanke, Steven R., Chen, Lin-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909677/
https://ncbi.nlm.nih.gov/pubmed/23606331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24573
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