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Daunomycin, an antitumor DNA intercalator, influences histone–DNA interactions

Although daunomycin and adriamycin are considered effective antitumor drugs and have been used in the clinic for over 40 years, their mechanism of action is still a matter of debate. We investigated the influence of daunomycin on interaction between linker or core histones and DNA in live HeLa cells...

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Detaylı Bibliyografya
Asıl Yazarlar: Wójcik, Krzysztof, Zarębski, Mirosław, Cossarizza, Andrea, Dobrucki, Jurek W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909551/
https://ncbi.nlm.nih.gov/pubmed/23792590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.25328
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