Stabilized complexes of epidermal growth factor and its receptor on the cell surface stimulate RNA synthesis but not mitogenesis.

Treatment of mouse fibroblasts, prelabeled at 4 degrees C with 125I-labeled epidermal growth factor (EGF), with the lectin concanavalin A (Con A) stabilized the 125I-labeled EGF-receptor complex to dissociation and prevented receptor-mediated endocytosis; after 5 hr at 37 degrees C, approximately 50...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Wakshull, E M, Wharton, W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417223/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8513
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!