Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

Signal transducer and activator of transcription (STAT) proteins perform key roles in mediating signaling by cytokines and growth factors, including platelet-derived growth factor (PDGF). In addition, Src family kinases activate STAT signaling and are required for PDGF-induced mitogenesis in normal...

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Autors principals: Bowman, Tammy, Broome, Martin A., Sinibaldi, Dominic, Wharton, Walker, Pledger, W. J., Sedivy, John M., Irby, Rosalyn, Yeatman, Timothy, Courtneidge, Sara A., Jove, Richard
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC34666/
https://ncbi.nlm.nih.gov/pubmed/11404481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131568898
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