Accelerated Repair and Reduced Mutagenicity of DNA Damage Induced by Cigarette Smoke in Human Bronchial Cells Transfected with E.coli Formamidopyrimidine DNA Glycosylase

Cigarette smoke (CS) is associated to a number of pathologies including lung cancer. Its mutagenic and carcinogenic effects are partially linked to the presence of reactive oxygen species and polycyclic aromatic hydrocarbons (PAH) inducing DNA damage. The bacterial DNA repair enzyme formamidopyrimid...

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Detalhes bibliográficos
Main Authors: Foresta, Mara, Izzotti, Alberto, La Maestra, Sebastiano, Micale, Rosanna, Poggi, Alessandro, Vecchio, Donatella, Frosina, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909288/
https://ncbi.nlm.nih.gov/pubmed/24498234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087984
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