Accelerated Repair and Reduced Mutagenicity of DNA Damage Induced by Cigarette Smoke in Human Bronchial Cells Transfected with E.coli Formamidopyrimidine DNA Glycosylase

Cigarette smoke (CS) is associated to a number of pathologies including lung cancer. Its mutagenic and carcinogenic effects are partially linked to the presence of reactive oxygen species and polycyclic aromatic hydrocarbons (PAH) inducing DNA damage. The bacterial DNA repair enzyme formamidopyrimid...

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Detaylı Bibliyografya
Asıl Yazarlar: Foresta, Mara, Izzotti, Alberto, La Maestra, Sebastiano, Micale, Rosanna, Poggi, Alessandro, Vecchio, Donatella, Frosina, Guido
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909288/
https://ncbi.nlm.nih.gov/pubmed/24498234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087984
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