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Accelerated Repair and Reduced Mutagenicity of DNA Damage Induced by Cigarette Smoke in Human Bronchial Cells Transfected with E.coli Formamidopyrimidine DNA Glycosylase

Cigarette smoke (CS) is associated to a number of pathologies including lung cancer. Its mutagenic and carcinogenic effects are partially linked to the presence of reactive oxygen species and polycyclic aromatic hydrocarbons (PAH) inducing DNA damage. The bacterial DNA repair enzyme formamidopyrimid...

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書誌詳細
主要な著者: Foresta, Mara, Izzotti, Alberto, La Maestra, Sebastiano, Micale, Rosanna, Poggi, Alessandro, Vecchio, Donatella, Frosina, Guido
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909288/
https://ncbi.nlm.nih.gov/pubmed/24498234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087984
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