Modification and secretion of human interleukin 2 produced in insect cells by a baculovirus expression vector.
A cDNA coding for human interleukin 2 (IL-2) was inserted into the genome of Autographa californica nuclear polyhedrosis virus adjacent to the polyhedrin promoter. Cells infected with recombinant virus produced high levels of Mr 15,500 IL-2 polypeptide, the majority of which was secreted into the cu...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1985
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3878519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8404 |
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