Modification and secretion of human interleukin 2 produced in insect cells by a baculovirus expression vector.

A cDNA coding for human interleukin 2 (IL-2) was inserted into the genome of Autographa californica nuclear polyhedrosis virus adjacent to the polyhedrin promoter. Cells infected with recombinant virus produced high levels of Mr 15,500 IL-2 polypeptide, the majority of which was secreted into the cu...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Smith, G E, Ju, G, Ericson, B L, Moschera, J, Lahm, H W, Chizzonite, R, Summers, M D
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1985
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3878519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8404
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