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Modification and secretion of human interleukin 2 produced in insect cells by a baculovirus expression vector.

A cDNA coding for human interleukin 2 (IL-2) was inserted into the genome of Autographa californica nuclear polyhedrosis virus adjacent to the polyhedrin promoter. Cells infected with recombinant virus produced high levels of Mr 15,500 IL-2 polypeptide, the majority of which was secreted into the cu...

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Autors principals: Smith, G E, Ju, G, Ericson, B L, Moschera, J, Lahm, H W, Chizzonite, R, Summers, M D
Format: Artigo
Idioma:Inglês
Publicat: 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC390924/
https://ncbi.nlm.nih.gov/pubmed/3878519
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