A Single Sfp-Type Phosphopantetheinyl Transferase Plays a Major Role in the Biosynthesis of PKS and NRPS Derived Metabolites in Streptomyces ambofaciens ATCC23877

The phosphopantetheinyl transferases (PPTases) are responsible for the activation of the carrier protein domains of the polyketide synthases (PKS), non ribosomal peptide synthases (NRPS) and fatty acid synthases (FAS). The analysis of the Streptomyces ambofaciens ATCC23877 genome has revealed the pr...

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Autori principali: Bunet, Robert, Riclea, Ramona, Laureti, Luisa, Hôtel, Laurence, Paris, Cédric, Girardet, Jean-Michel, Spiteller, Dieter, Dickschat, Jeroen S., Leblond, Pierre, Aigle, Bertrand
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909215/
https://ncbi.nlm.nih.gov/pubmed/24498152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087607
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