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Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens

Signaling molecule receptors play a central role in quorum sensing and in the coordination onset of specialized metabolite biosynthesis in Streptomyces due to their dual function in signal detection and gene expression control through DNA-binding in the promoter region of their target genes. In Stre...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Vicente, Cláudia M., Girardet, Jean-Michel, Hôtel, Laurence, Aigle, Bertrand
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343708/
https://ncbi.nlm.nih.gov/pubmed/32714286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01255
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