New Insights into the In Silico Prediction of HIV Protease Resistance to Nelfinavir

The Human Immunodeficiency Virus type 1 protease enzyme (HIV-1 PR) is one of the most important targets of antiretroviral therapy used in the treatment of AIDS patients. The success of protease-inhibitors (PIs), however, is often limited by the emergence of protease mutations that can confer resista...

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Autori principali: Antunes, Dinler A., Rigo, Maurício M., Sinigaglia, Marialva, de Medeiros, Rúbia M., Junqueira, Dennis M., Almeida, Sabrina E. M., Vieira, Gustavo F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909182/
https://ncbi.nlm.nih.gov/pubmed/24498124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087520
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