Structural Allele-Specific Patterns Adopted by Epitopes in the MHC-I Cleft and Reconstruction of MHC:peptide Complexes to Cross-Reactivity Assessment

The immune system is engaged in a constant antigenic surveillance through the Major Histocompatibility Complex (MHC) class I antigen presentation pathway. This is an efficient mechanism for detection of intracellular infections, especially viral ones. In this work we describe conformational patterns...

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Main Authors: Antunes, Dinler A., Vieira, Gustavo F., Rigo, Maurício M., Cibulski, Samuel P., Sinigaglia, Marialva, Chies, José A. B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860844/
https://ncbi.nlm.nih.gov/pubmed/20442757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010353
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