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New Insights into the In Silico Prediction of HIV Protease Resistance to Nelfinavir
The Human Immunodeficiency Virus type 1 protease enzyme (HIV-1 PR) is one of the most important targets of antiretroviral therapy used in the treatment of AIDS patients. The success of protease-inhibitors (PIs), however, is often limited by the emergence of protease mutations that can confer resista...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909182/ https://ncbi.nlm.nih.gov/pubmed/24498124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087520 |
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