Effects of phospholipids and ADP-ribosylation on GTP hydrolysis by Escherichia coli-synthesized Ha-ras-encoded p21.

The Ha-ras protooncogene product p21, which may be involved in control of cellular growth, is a membrane protein that binds guanine nucleotides and hydrolyzes GTP. p21 GTPase activity is stimulated by lysophosphatidylcholine; a delay in activation was observed unless p21 was incubated with the phosp...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Tsai, S C, Adamik, R, Moss, J, Vaughan, M, Manne, V, Kung, H F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3001695/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8310
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