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The Effect of a Cyclooxygenase 2 Inhibitor on Early Degenerated Human Nucleus Pulposus Explants

Study Design Preclinical in vitro culture of human degenerated nucleus pulposus (NP) tissue. Objective Cyclooxygenase 2 inhibitors (e.g., celecoxib) inhibit prostaglandin E(2) (PGE(2)) production, and they have been shown to upregulate regeneration of articular cartilage. In this study, we developed...

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Auteurs principaux: van Dijk, Bart, Potier, Esther, Licht, Ruud, Creemers, Laura, Ito, Keita
Format: Artigo
Langue:Inglês
Publié: Georg Thieme Verlag KG 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908972/
https://ncbi.nlm.nih.gov/pubmed/24494179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0033-1359724
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