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Hypotonicity differentially affects inflammatory marker production by nucleus pulposus tissue in simulated disc degeneration versus herniation

Inflammatory cytokines play an important role in intervertebral disc degeneration. Although largely produced by immune cells, nucleus pulposus (NP) cells can also secrete them under various conditions, for example, under free swelling. Thus, tissue hypotonicity may be an inflammatory trigger for NP...

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Bibliografiske detaljer
Udgivet i:J Orthop Res
Main Authors: Mouser, Vivian H. M., Arkesteijn, Irene T. M., van Dijk, Bart G. M., Wuertz‐Kozak, Karin, Ito, Keita
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593810/
https://ncbi.nlm.nih.gov/pubmed/30835843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24268
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