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Using notochordal cells of developmental origin to stimulate nucleus pulposus cells and bone marrow stromal cells for intervertebral disc regeneration

PURPOSE: Bone marrow stromal cells (BMSCs) have been proposed to complement the declining population of nucleus pulposus cells (NPCs) found in a degenerative intervertebral disc. Although able to stop degeneration, they could not produce enough matrix to restore a healthy state. Looking at developme...

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Bibliographic Details
Main Authors: Potier, Esther, Ito, Keita
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940810/
https://ncbi.nlm.nih.gov/pubmed/24258526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-013-3107-8
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