Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

The herpes simplex virus DNA polymerase provides an excellent model for studies of eukaryotic replicative polymerases. We report here the nucleotide sequence of the gene which encodes this enzyme. The gene includes a 3705-base-pair major open reading frame capable of encoding a Mr 136,519 polypeptid...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gibbs, J S, Chiou, H C, Hall, J D, Mount, D W, Retondo, M J, Weller, S K, Coen, D M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390892/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2999787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.7969
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