Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

The herpes simplex virus DNA polymerase provides an excellent model for studies of eukaryotic replicative polymerases. We report here the nucleotide sequence of the gene which encodes this enzyme. The gene includes a 3705-base-pair major open reading frame capable of encoding a Mr 136,519 polypeptid...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Gibbs, J S, Chiou, H C, Hall, J D, Mount, D W, Retondo, M J, Weller, S K, Coen, D M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1985
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390892/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2999787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.7969
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