Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

The herpes simplex virus DNA polymerase provides an excellent model for studies of eukaryotic replicative polymerases. We report here the nucleotide sequence of the gene which encodes this enzyme. The gene includes a 3705-base-pair major open reading frame capable of encoding a Mr 136,519 polypeptid...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gibbs, J S, Chiou, H C, Hall, J D, Mount, D W, Retondo, M J, Weller, S K, Coen, D M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390892/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2999787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.7969
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